The pediatrics lab at Maastricht University focuses on the role of inflammatory stress in fetal and neonatal organs, including intra-amniotic infections, perinatal hypoxia-ischemia and mechanical ventilation, and how this disrupts their development. Associate Professor Tim Wolfs, Doctor Daan Ophelders and Doctor Reint Jellema bring longstanding expertise on pre-clinical ovine models for injury of vulnerable neonates, in which the consequences of inflammation stress are studied across the entire life span. These models form a solid basis for clinical translation and enable us to investigate potential clinical immune-modulatory and regenerative interventions, and cell-based therapeutics in particular, to treat adverse outcomes of babies.
in vivo validation of ArtPlac in preterm born lambs
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